Cargando…

Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder

BACKGROUND: Meta-analyses have identified serum levels of brain-derived neurotrophic factor (BDNF) as a potential biomarker for major depressive disorder (MDD). However, at the time, commercially available human ELISA kits are unable to distinguish between proBDNF (precursor of BDNF) and mature BDNF...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoshida, Taisuke, Ishikawa, Masatomo, Niitsu, Tomihisa, Nakazato, Michiko, Watanabe, Hiroyuki, Shiraishi, Tetsuya, Shiina, Akihiro, Hashimoto, Tasuku, Kanahara, Nobuhisa, Hasegawa, Tadashi, Enohara, Masayo, Kimura, Atsushi, Iyo, Masaomi, Hashimoto, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411809/ https://www.ncbi.nlm.nih.gov/pubmed/22880079 http://dx.doi.org/10.1371/journal.pone.0042676

Ejemplares similares

Correction: Decreased Serum Levels of Mature Brain-Derived Neurotrophic Factor (BDNF), but Not Its Precursor proBDNF, in Patients with Major Depressive Disorder
por: Yoshida, Taisuke, et al.
Publicado: (2013)

A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia
por: Shiina, Akihiro, et al.
Publicado: (2010)

Treatment of refractory catatonic schizophrenia with low dose aripiprazole
por: Sasaki, Tsuyoshi, et al.
Publicado: (2012)

Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF
por: Le Blanc, Jessica, et al.
Publicado: (2020)

Effect of mirtazapine versus selective serotonin reuptake inhibitors on benzodiazepine use in patients with major depressive disorder: a pragmatic, multicenter, open-label, randomized, active-controlled, 24-week trial
por: Hashimoto, Tasuku, et al.
Publicado: (2016)

Altered expression of BDNF, BDNF pro-peptide and their precursor proBDNF in brain and liver tissues from psychiatric disorders: rethinking the brain–liver axis
por: Yang, B, et al.
Publicado: (2017)

An Open Study of Sulforaphane-rich Broccoli Sprout Extract in Patients with Schizophrenia
por: Shiina, Akihiro, et al.
Publicado: (2015)

Relationship between perception and anxiety about COVID-19 infection and risk behaviors for spreading infection: A national survey in Japan
por: Shiina, Akihiro, et al.
Publicado: (2020)

Perception of and anxiety about COVID-19 infection and risk behaviors for spreading infection: an international comparison
por: Shiina, Akihiro, et al.
Publicado: (2021)

Tipepidine in adolescent patients with depression: a 4 week, open-label, preliminary study
por: Sasaki, Tsuyoshi, et al.
Publicado: (2014)

Decrease in the Ratio proBDNF/BDNF in the Urine of Aging Female Patients with OAB
por: Covarrubias, Claudia, et al.
Publicado: (2023)

Psychological Distress Symptoms Associated With Life Events in Patients With Bipolar Disorder: A Cross-Sectional Study
por: Sato, Aiko, et al.
Publicado: (2018)

Vulnerable combinations of functional dopaminergic polymorphisms to late-onset treatment resistant schizophrenia
por: Oishi, Kengo, et al.
Publicado: (2018)

Serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol levels in chronic schizophrenia
por: Yoshimura, Reiji, et al.
Publicado: (2016)

Association of Plasma Pro-Brain-Derived Neurotrophic Factor (proBDNF)/Mature Brain-Derived Neurotrophic Factor (mBDNF) Levels with BDNF Gene Val66Met Polymorphism in Alcohol Dependence
por: Mo, Min, et al.
Publicado: (2021)

Tipepidine in children with attention deficit/hyperactivity disorder: a 4-week, open-label, preliminary study
por: Sasaki, Tsuyoshi, et al.
Publicado: (2014)

Rapid Increases in proBDNF after Pilocarpine-Induced Status Epilepticus in Mice Are Associated with Reduced proBDNF Cleavage Machinery123
por: Thomas, Ajay X., et al.
Publicado: (2016)

Need for self-medication using over-the-counter psychoactive agents: A national survey in Japan
por: Shiina, Akihiro, et al.
Publicado: (2021)

Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex
por: Gibon, Julien, et al.
Publicado: (2016)

BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism
por: Robinson-Agramonte, Maria de los Angeles, et al.
Publicado: (2022)

Increased Serum Levels of Oxytocin in ‘Treatment Resistant Depression in Adolescents (TRDIA)’ Group
por: Sasaki, Tsuyoshi, et al.
Publicado: (2016)

Proteolysis of proBDNF Is a Key Regulator in the Formation of Memory
por: Barnes, Philip, et al.
Publicado: (2008)

proBDNF inhibits the proliferation and migration of OLN-93 oligodendrocytes
por: Liu, Shen, et al.
Publicado: (2018)

ProBDNF as an Indicator of Improvement among Women with Depressive Episodes
por: Zwolińska, Weronika, et al.
Publicado: (2022)

Proteolytic cleavage of proBDNF into mature BDNF in the basolateral amygdala is necessary for defeat-induced social avoidance
por: Dulka, Brooke N., et al.
Publicado: (2016)

Serum mBDNF and ProBDNF Expression Levels as Diagnosis Clue for Early Stage Parkinson's Disease
por: Yi, Xu, et al.
Publicado: (2021)

Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice
por: Xue, Ziyi, et al.
Publicado: (2022)

Autistic traits and cognitive profiles of treatment-resistant schizophrenia()
por: Nakata, Yusuke, et al.
Publicado: (2020)

Acute stress alters transcript expression pattern and reduces processing of proBDNF to mature BDNF in Dicentrarchus labrax
por: Tognoli, Chiara, et al.
Publicado: (2010)

Serum proBDNF/BDNF and response to fluvoxamine in drug-naïve first-episode major depressive disorder patients
por: Yoshimura, Reiji, et al.
Publicado: (2014)

Evaluation of HIF-1 Involvement in the BDNF and ProBDNF Signaling Pathways among Obstructive Sleep Apnea Patients
por: Gabryelska, Agata, et al.
Publicado: (2022)

BDNF and proBDNF Serum Protein Levels in Obstructive Sleep Apnea Patients and Their Involvement in Insomnia and Depression Symptoms
por: Gabryelska, Agata, et al.
Publicado: (2022)

Changes in Plasma TPH2, GDNF, Trk-b, BDNF, and proBDNF in People Who Died by Suicide
por: Liu, Xiaoyu, et al.
Publicado: (2023)

Increased Hippocampal ProBDNF Contributes to Memory Impairments in Aged Mice
por: Buhusi, Mona, et al.
Publicado: (2017)

Influence of Quadrato Motor Training on Salivary proNGF and proBDNF
por: Caserta, Micaela, et al.
Publicado: (2019)

ProBDNF and Brain-Derived Neurotrophic Factor Prodomain Differently Modulate Acetylcholine Release in Regenerating and Mature Mouse Motor Synapses
por: Bogacheva, Polina O., et al.
Publicado: (2022)

Changes in Self-Regulation-Related Prefrontal Activities in Eating Disorders: A Near Infrared Spectroscopy Study
por: Sutoh, Chihiro, et al.
Publicado: (2013)

ProBDNF Collapses Neurite Outgrowth of Primary Neurons by Activating RhoA
por: Sun, Ying, et al.
Publicado: (2012)

Requirements of Postnatal proBDNF in the Hippocampus for Spatial Memory Consolidation and Neural Function
por: Sun, Wei, et al.
Publicado: (2021)

Differences in the Relative Abundance of ProBDNF and Mature BDNF in A549 and H1299 Human Lung Cancer Cell Media
por: Dorandish, Sadaf, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ctmkegmbhfhftb4lucqm2kac8h