Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING

The innate immune system senses infection by detecting evolutionarily conserved molecules essential for microbial survival or abnormal location of molecules. Here we demonstrate the existence of a novel innate detection mechanism, which is induced by fusion between viral envelopes and target cells....

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Detalles Bibliográficos
Autores principales: Holm, Christian K, Jensen, Søren B, Jakobsen, Martin R, Cheshenko, Natalia, Horan, Kristy A, Moeller, Hanne B, Gonzalez-Dosal, Regina, Rasmussen, Simon B, Christensen, Maria H., Yarovinsky, Timur O, Rixon, Frazer J, Herold, Betsy C, Fitzgerald, Katherine A, Paludan, Søren R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411909/
https://www.ncbi.nlm.nih.gov/pubmed/22706339
http://dx.doi.org/10.1038/ni.2350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411909/
https://www.ncbi.nlm.nih.gov/pubmed/22706339
http://dx.doi.org/10.1038/ni.2350

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