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Contractile Activity Regulates Inducible Nitric Oxide Synthase Expression and NO(i) Production in Cardiomyocytes via a FAK-Dependent Signaling Pathway
Intracellular nitric oxide (NO(i)) is a physiological regulator of excitation-contraction coupling, but is also involved in the development of cardiac dysfunction during hypertrophy and heart failure. To determine whether contractile activity regulates nitric oxide synthase (NOS) expression, spontan...
Autores principales: | Chu, Miensheng, Koshman, Yevgeniya, Iyengar, Rekha, Kim, Taehoon, Russell, Brenda, Samarel, Allen M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412095/ https://www.ncbi.nlm.nih.gov/pubmed/22900166 http://dx.doi.org/10.1155/2012/473410 |
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