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Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process
The NF-κB signaling system and the autophagic degradation pathway are crucial cellular survival mechanisms, both being well conserved during evolution. Emerging studies have indicated that the IKK/NF-κB signaling axis regulates autophagy in a context-dependent manner. IKK complex and NF-κB can enhan...
Autores principales: | Salminen, Antero, Hyttinen, Juha M. T., Kauppinen, Anu, Kaarniranta, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412117/ https://www.ncbi.nlm.nih.gov/pubmed/22899934 http://dx.doi.org/10.1155/2012/849541 |
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