Attenuated Salmonella typhimurium delivering DNA vaccine encoding duck enteritis virus UL24 induced systemic and mucosal immune responses and conferred good protection against challenge

Orally delivered DNA vaccines against duck enteritis virus (DEV) were developed using live attenuated Salmonella typhimurium (SL7207) as a carrier and Escherichia coli heat labile enterotoxin B subunit (LTB) as a mucosal adjuvant. DNA vaccine plasmids pVAX-UL24 and pVAX-LTB-UL24 were constructed and...

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Detalles Bibliográficos
Autores principales: Yu, Xia, Jia, Renyong, Huang, Juan, Shu, Bin, Zhu, Dekang, Liu, Qing, Gao, Xinghong, Lin, Meng, Yin, Zhongqiong, Wang, Mingshu, Chen, Shun, Wang, Yin, Chen, Xiaoyue, Cheng, Anchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412168/
https://www.ncbi.nlm.nih.gov/pubmed/22770566
http://dx.doi.org/10.1186/1297-9716-43-56

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