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The critical role of S-lactoylglutathione formation during methylglyoxal detoxification in Escherichia coli

Survival of exposure to methylglyoxal (MG) in Gram-negative pathogens is largely dependent upon the operation of the glutathione-dependent glyoxalase system, consisting of two enzymes, GlxI (gloA) and GlxII (gloB). In addition, the activation of the KefGB potassium efflux system is maintained closed...

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Detalles Bibliográficos
Autores principales: Ozyamak, Ertan, Black, Susan S, Walker, Claire A, MacLean, Morag J, Bartlett, Wendy, Miller, Samantha, Booth, Ian R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412212/
https://www.ncbi.nlm.nih.gov/pubmed/21143325
http://dx.doi.org/10.1111/j.1365-2958.2010.07426.x