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Akt and mTOR in B Cell Activation and Differentiation

Activation of phosphoinositide 3-kinase (PI3K) is required for B cell proliferation and survival. PI3K signaling also controls key aspects of B cell differentiation. Upon engagement of the B cell receptor (BCR), PI3K activation promotes Ca(2+) mobilization and activation of NFκB-dependent transcript...

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Detalles Bibliográficos
Autores principales:	Limon, Jose J., Fruman, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412259/ https://www.ncbi.nlm.nih.gov/pubmed/22888331 http://dx.doi.org/10.3389/fimmu.2012.00228

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