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Discovery and Replication of Gene Influences on Brain Structure Using LASSO Regression

We implemented least absolute shrinkage and selection operator (LASSO) regression to evaluate gene effects in genome-wide association studies (GWAS) of brain images, using an MRI-derived temporal lobe volume measure from 729 subjects scanned as part of the Alzheimer’s Disease Neuroimaging Initiative...

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Detalles Bibliográficos
Autores principales:	Kohannim, Omid, Hibar, Derrek P., Stein, Jason L., Jahanshad, Neda, Hua, Xue, Rajagopalan, Priya, Toga, Arthur W., Jack, Clifford R., Weiner, Michael W., de Zubicaray, Greig I., McMahon, Katie L., Hansell, Narelle K., Martin, Nicholas G., Wright, Margaret J., Thompson, Paul M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412288/ https://www.ncbi.nlm.nih.gov/pubmed/22888310 http://dx.doi.org/10.3389/fnins.2012.00115

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