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Basal and Regulatory Promoter Studies of the AKR1C3 Gene in Relation to Prostate Cancer
Background: Human 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5) formally known as aldo-keto reductase 1C3 (AKR1C3) play a major role in the formation and metabolism of androgens. The enzyme is highly expressed in the prostate gland and previous studies indicate that genetic variation in the AKR...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Research Foundation
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412290/ https://www.ncbi.nlm.nih.gov/pubmed/22888320 http://dx.doi.org/10.3389/fphar.2012.00151 |