Cargando…

Transfer of 4-hydroxynonenal from parasitized to non-parasitized erythrocytes in rosettes. Proposed role in severe malaria anemia

Severe anaemia is a life-threatening complication of falciparum malaria associated with loss of predominantly non-parasitized red blood cells (npRBCs). This poorly elucidated process might be influenced by (i) rosettes, i.e. npRBCs cytoadherent to haemozoin-containing parasitized RBCs (pRBCs) and (i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uyoga, Sophie, Skorokhod, Oleksii A, Opiyo, Michael, Orori, Emily N, Williams, Thomas N, Arese, Paolo, Schwarzer, Evelin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Red Cells and Iron
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412292/ https://www.ncbi.nlm.nih.gov/pubmed/22352722 http://dx.doi.org/10.1111/j.1365-2141.2011.09015.x

Ejemplares similares

Role of the Lipoperoxidation Product 4-Hydroxynonenal in the Pathogenesis of Severe Malaria Anemia and Malaria Immunodepression
por: Schwarzer, Evelin, et al.
Publicado: (2015)

Preferential binding of 4-hydroxynonenal to lysine residues in specific parasite proteins in plakortin-treated Plasmodium falciparum-parasitized red blood cells
por: Schwarzer, Evelin, et al.
Publicado: (2015)

Simultaneous determination of phagocytosis of Plasmodium falciparum-parasitized and non-parasitized red blood cells by flow cytometry
por: Gallo, Valentina, et al.
Publicado: (2012)

Transfer of 4-hydroxynonenal, a inhibitory hemozoin (HZ) product, from HZ or HZ-laden phagocytes to developing human erythroid cells. A model for erythropoiesis inhibition in malaria anemia
por: Skorokhod, Oleksii A, et al.
Publicado: (2010)

Measurement of erythrocyte membrane mannoses to assess splenic function
por: Cao, Huan, et al.
Publicado: (2022)

Safety and benefits of interventions to increase folate status in malaria‐endemic areas
por: Verhoef, Hans, et al.
Publicado: (2017)

Simultaneous adjunctive treatment of malaria and its coevolved genetic disorder sickle cell anemia
por: Safeukui, Innocent, et al.
Publicado: (2023)

Cytoadherence in paediatric malaria: ABO blood group, CD36, and ICAM1 expression and severe Plasmodium falciparum infection
por: Cserti-Gazdewich, Christine M, et al.
Publicado: (2012)

Malaria Pigment Hemozoin Impairs GM-CSF Receptor Expression and Function by 4-Hydroxynonenal
por: Skorokhod, Oleksii, et al.
Publicado: (2021)

Elucidating parasite and host-cell factors enabling Babesia infection in sickle red cells under hypoxic/hyperoxic conditions
por: Beri, Divya, et al.
Publicado: (2022)

Kindlin-3 deficiency leads to impaired erythropoiesis and erythrocyte cytoskeleton
por: Szpak, Dorota, et al.
Publicado: (2023)

Proteome alterations in erythrocytes with PIEZO1 gain-of-function mutations
por: Andolfo, Immacolata, et al.
Publicado: (2023)

Computer vision quantitation of erythrocyte shape abnormalities provides diagnostic, prognostic, and mechanistic insight
por: Foy, Brody H., et al.
Publicado: (2023)

Hepcidin is the major predictor of erythrocyte iron incorporation in anemic African children
por: Prentice, Andrew M., et al.
Publicado: (2012)

Splenectomy improves erythrocyte functionality in spherocytosis based on septin abundance, but not maturation defects
por: Cloos, Anne-Sophie, et al.
Publicado: (2023)

Membrane bending and sphingomyelinase-associated, sulfatide-dependent hypoxic adhesion of sickle mature erythrocytes
por: Goreke, Utku, et al.
Publicado: (2023)

Autoimmune hemolytic anemia during pregnancy and puerperium: an international multicenter experience
por: Fattizzo, Bruno, et al.
Publicado: (2023)

Safety and benefits of antenatal oral iron supplementation in low‐income countries: a review
por: Mwangi, Martin N., et al.
Publicado: (2017)

Oxidative stress and phosphatidylserine exposure in red cells from patients with sickle cell anaemia
por: Hannemann, Anke, et al.
Publicado: (2018)

Risk factors for high cerebral blood flow velocity and death in Kenyan children with Sickle Cell Anaemia: role of haemoglobin oxygen saturation and febrile illness
por: Makani, Julie, et al.
Publicado: (2009)

Natural history and variability in albuminuria in pediatric and murine sickle cell anemia
por: Kasztan, Malgorzata, et al.
Publicado: (2023)

Bacteraemia in sickle cell anaemia is associated with low haemoglobin: a report of 890 admissions to a tertiary hospital in Tanzania
por: Makani, Julie, et al.
Publicado: (2015)

Vasculo‐toxic and pro‐inflammatory action of unbound haemoglobin, haem and iron in transfusion‐dependent patients with haemolytic anaemias
por: Vinchi, Francesca, et al.
Publicado: (2021)

Azacitidine is a potential therapeutic drug for pyridoxine-refractory female X-linked sideroblastic anemia
por: Morimoto, Yuki, et al.
Publicado: (2022)

Structural connectivity mediates the relationship between blood oxygenation and cognitive function in sickle cell anemia
por: Clayden, Jonathan D., et al.
Publicado: (2022)

Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia
por: Kumkhaek, Chutima, et al.
Publicado: (2008)

A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease
por: Vichinsky, Elliott, et al.
Publicado: (2007)

Long-term safety and efficacy of deferasirox (Exjade®) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease
por: Vichinsky, Elliott, et al.
Publicado: (2011)

Increased levels of the inflammatory biomarker C-reactive protein at baseline are associated with childhood sickle cell vasocclusive crises
por: Krishnan, Suba, et al.
Publicado: (2010)

Efficacy and safety of deferasirox doses of >30 mg/kg per d in patients with transfusion-dependent anaemia and iron overload
por: Taher, Ali, et al.
Publicado: (2009)

Haptoglobin, alpha‐thalassaemia and glucose‐6‐phosphate dehydrogenase polymorphisms and risk of abnormal transcranial Doppler among patients with sickle cell anaemia in Tanzania
por: Cox, Sharon E., et al.
Publicado: (2014)

Epistasis and the sensitivity of phenotypic screens for beta thalassaemia
por: Penman, Bridget S, et al.
Publicado: (2015)

The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels
por: Patel, Neeta, et al.
Publicado: (2014)

An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin
por: Carrancio, Soraya, et al.
Publicado: (2014)

Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co-express gamma and beta globins
por: Yang, Cheng-Tao, et al.
Publicado: (2014)

A novel 33‐Gene targeted resequencing panel provides accurate, clinical‐grade diagnosis and improves patient management for rare inherited anaemias
por: Roy, Noémi B. A., et al.
Publicado: (2016)

Iron overload across the spectrum of non‐transfusion‐dependent thalassaemias: role of erythropoiesis, splenectomy and transfusions
por: Porter, John B., et al.
Publicado: (2016)

Quantitative sensory testing in children with sickle cell disease: additional insights and future possibilities
por: Miller, Robin E., et al.
Publicado: (2019)

Ticagrelor does not impact patient‐reported pain in young adults with sickle cell disease: a multicentre, randomised phase IIb study
por: Kanter, Julie, et al.
Publicado: (2018)

MIR29B mediates epigenetic mechanisms of HBG gene activation
por: Starlard‐Davenport, Athena, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5sdshtvkobbcn1l11p41gheq38