Aryl Hydrocarbon Receptor-Mediated Perturbations in Gene Expression during Early Stages of CD4(+) T-cell Differentiation

Activation of the aryl hydrocarbon receptor (AhR) by its prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mediates potent suppression of T-cell dependent immune responses. The suppressive effects of TCDD occur early during CD4(+) T-cell differentiation in the absence of effects on prol...

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Detalles Bibliográficos
Autores principales: Rohlman, Diana, Pham, Duy, Yu, Zhen, Steppan, Linda B., Kerkvliet, Nancy I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412388/
https://www.ncbi.nlm.nih.gov/pubmed/22888330
http://dx.doi.org/10.3389/fimmu.2012.00223

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