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Spatial regulation of translation through RNA localization
RNA localization is a mechanism to post-transcriptionally regulate gene expression. Eukaryotic organisms ranging from fungi to mammals localize mRNAs to spatially restrict synthesis of specific proteins to distinct regions of the cytoplasm. In this review, we provide a general summary of RNA localiz...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of 1000 Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412389/ https://www.ncbi.nlm.nih.gov/pubmed/22912650 http://dx.doi.org/10.3410/B4-16 |
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author | Gonsalvez, Graydon B. Long, Roy M. |
author_facet | Gonsalvez, Graydon B. Long, Roy M. |
author_sort | Gonsalvez, Graydon B. |
collection | PubMed |
description | RNA localization is a mechanism to post-transcriptionally regulate gene expression. Eukaryotic organisms ranging from fungi to mammals localize mRNAs to spatially restrict synthesis of specific proteins to distinct regions of the cytoplasm. In this review, we provide a general summary of RNA localization pathways in Saccharomyces cerevisiae, Xenopus, Drosophila and mammalian neurons. |
format | Online Article Text |
id | pubmed-3412389 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Faculty of 1000 Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-34123892012-08-21 Spatial regulation of translation through RNA localization Gonsalvez, Graydon B. Long, Roy M. F1000 Biol Rep Review Article RNA localization is a mechanism to post-transcriptionally regulate gene expression. Eukaryotic organisms ranging from fungi to mammals localize mRNAs to spatially restrict synthesis of specific proteins to distinct regions of the cytoplasm. In this review, we provide a general summary of RNA localization pathways in Saccharomyces cerevisiae, Xenopus, Drosophila and mammalian neurons. Faculty of 1000 Ltd 2012-08-01 /pmc/articles/PMC3412389/ /pubmed/22912650 http://dx.doi.org/10.3410/B4-16 Text en © 2012 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes |
spellingShingle | Review Article Gonsalvez, Graydon B. Long, Roy M. Spatial regulation of translation through RNA localization |
title | Spatial regulation of translation through RNA
localization |
title_full | Spatial regulation of translation through RNA
localization |
title_fullStr | Spatial regulation of translation through RNA
localization |
title_full_unstemmed | Spatial regulation of translation through RNA
localization |
title_short | Spatial regulation of translation through RNA
localization |
title_sort | spatial regulation of translation through rna
localization |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412389/ https://www.ncbi.nlm.nih.gov/pubmed/22912650 http://dx.doi.org/10.3410/B4-16 |
work_keys_str_mv | AT gonsalvezgraydonb spatialregulationoftranslationthroughrnalocalization AT longroym spatialregulationoftranslationthroughrnalocalization |