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MyD88 Signaling in B Cells Regulates the Production of Th1-dependent Antibodies to AAV
The administration of recombinant adeno-associated viral vectors (rAAV) for gene transfer induces strong humoral responses through mechanisms that remain incompletely characterized. To investigate the links between innate and adaptive immune responses to the vector, rAAVs were injected intravenously...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412489/ https://www.ncbi.nlm.nih.gov/pubmed/22643865 http://dx.doi.org/10.1038/mt.2012.101 |