MyD88 Signaling in B Cells Regulates the Production of Th1-dependent Antibodies to AAV

The administration of recombinant adeno-associated viral vectors (rAAV) for gene transfer induces strong humoral responses through mechanisms that remain incompletely characterized. To investigate the links between innate and adaptive immune responses to the vector, rAAVs were injected intravenously...

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Detalles Bibliográficos
Autores principales: Sudres, Muriel, Ciré, Séverine, Vasseur, Virginie, Brault, Léa, Da Rocha, Sylvie, Boisgérault, Florence, Le Bec, Christine, Gross, David Alexandre, Blouin, Véronique, Ryffel, Bernard, Galy, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412489/
https://www.ncbi.nlm.nih.gov/pubmed/22643865
http://dx.doi.org/10.1038/mt.2012.101

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