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Targeting the Hemoglobin Scavenger receptor CD163 in Macrophages Highly Increases the Anti-inflammatory Potency of Dexamethasone
Synthetic glucocorticoids are potent anti-inflammatory drugs but serious side effects such as bone mobilization, muscle mass loss, immunosuppression, and metabolic alterations make glucocorticoid therapy a difficult balance. The therapeutic anti-inflammatory effect of glucocorticoids relies largely...
Autores principales: | Graversen, Jonas H, Svendsen, Pia, Dagnæs-Hansen, Frederik, Dal, Jakob, Anton, Gabriele, Etzerodt, Anders, Petersen, Mikkel D, Christensen, Peter A, Møller, Holger J, Moestrup, Søren K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412497/ https://www.ncbi.nlm.nih.gov/pubmed/22643864 http://dx.doi.org/10.1038/mt.2012.103 |
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