Genomic copy number alterations in clear cell renal carcinoma: associations with case characteristics and mechanisms of VHL gene inactivation

Array comparative genomic hybridization was used to identify copy number alterations in clear cell renal cell carcinoma (ccRCC) patient tumors to identify associations with patient/clinical characteristics. Of 763 ccRCC patients, 412 (54%) provided frozen biopsies. Clones were analyzed for significa...

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Detalles Bibliográficos
Autores principales: Moore, L E, Jaeger, E, Nickerson, M L, Brennan, P, De Vries, S, Roy, R, Toro, J, Li, H, Karami, S, Lenz, P, Zaridze, D, Janout, V, Bencko, V, Navratilova, M, Szeszenia-Dabrowska, N, Mates, D, Linehan, W M, Merino, M, Simko, J, Pfeiffer, R, Boffetta, P, Hewitt, S, Rothman, N, Chow, W-H, Waldman, F M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412648/
https://www.ncbi.nlm.nih.gov/pubmed/23552698
http://dx.doi.org/10.1038/oncsis.2012.14

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