Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia

Acute myeloid leukemias (AMLs) are a heterogeneous group of diseases that are sustained by relatively rare leukemia-initiating cells (LICs) that exhibit diverse genetic and phenotypic properties. AML heterogeneity presents a major challenge to development of targeted therapies, and effective treatme...

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Detalles Bibliográficos
Autores principales: Boudreaux, S P, Ramirez-Herrick, A M, Duren, R P, Conneely, O M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412651/
https://www.ncbi.nlm.nih.gov/pubmed/23552735
http://dx.doi.org/10.1038/oncsis.2012.19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412651/
https://www.ncbi.nlm.nih.gov/pubmed/23552735
http://dx.doi.org/10.1038/oncsis.2012.19

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