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Evaluation of epigenetic modulation of cyclooxygenase-2 as a prognostic marker for hepatocellular carcinoma
Cyclooxygenases (COX-1 and 2) catalyze the first step in prostanoid biosynthesis. They are implicated in homeostatic processes with an important role in inflammation and carcinogenesis. In the liver, COX-2 expression is restricted to proliferation or dedifferentiation situations. The COX-2 promoter...
Autores principales: | Fernández-Alvarez, A, Llorente-Izquierdo, C, Mayoral, R, Agra, N, Boscá, L, Casado, M, Martín-Sanz, P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412654/ https://www.ncbi.nlm.nih.gov/pubmed/23552739 http://dx.doi.org/10.1038/oncsis.2012.23 |
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