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A Distinct Expression Pattern of the Long 3′-Untranslated Region Dicer mRNA and Its Implications for Posttranscriptional Regulation in Colorectal Cancer
OBJECTIVES: Reduced expression of Dicer is associated with global downregulation of microRNAs. Primary Dicer transcripts can be processed at two alternative polyadenylation sites, generating two pools of messenger RNAs (mRNAs) that carry either a long or a short 3′-untranslated regions (3′UTRs), tha...
Autores principales: | Hamaya, Yasushi, Kuriyama, Shigeru, Takai, Tetsunari, Yoshida, Ken-ichi, Yamada, Takanori, Sugimoto, Mitsushige, Osawa, Satoshi, Sugimoto, Ken, Miyajima, Hiroaki, Kanaoka, Shigeru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412679/ https://www.ncbi.nlm.nih.gov/pubmed/23238289 http://dx.doi.org/10.1038/ctg.2012.12 |
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