Exogenous erythropoietin administration attenuates intermittent hypoxia-induced cognitive deficits in a murine model of sleep apnea

BACKGROUND: In rodents, exposure to intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), is associated with neurobehavioral impairments, increased apoptosis in the hippocampus and cortex, as well as increased oxidant stress and inflammation. Such findings are markedly attenuated i...

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Detalles Bibliográficos
Autores principales: Dayyat, Ehab A, Zhang, Shelley X, Wang, Yang, Cheng, Zixi Jack, Gozal, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412695/
https://www.ncbi.nlm.nih.gov/pubmed/22759774
http://dx.doi.org/10.1186/1471-2202-13-77

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