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Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum

BACKGROUND: Anandamide (Arachidonoyl ethanolamide) is a potent bioactive lipid studied extensively in humans, which regulates several neurobehavioral processes including pain, feeding and memory. Bioactivity is terminated when hydrolyzed into free arachidonic acid and ethanolamine by the enzyme fatt...

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Detalles Bibliográficos
Autores principales: Neelamegan, Dhamodharan, Schoenhofen, Ian C, Richards, James C, Cox, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412733/
https://www.ncbi.nlm.nih.gov/pubmed/22730904
http://dx.doi.org/10.1186/1471-2180-12-124