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Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration

BACKGROUND: Increasing evidence links systemic inflammation to neuroinflammation and neurodegeneration. We previously found that systemic endotoxin, a TLR4 agonist or TNFα, increased blood TNFα that entered the brain activating microglia and persistent neuroinflammation. Further, we found that model...

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Detalles Bibliográficos
Autores principales:	Qin, Liya, Crews, Fulton T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412752/ https://www.ncbi.nlm.nih.gov/pubmed/22709825 http://dx.doi.org/10.1186/1742-2094-9-130

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