High-Throughput Screening and Rapid Inhibitor Triage Using an Infectious Chimeric Hepatitis C Virus

The recent development of a Hepatitis C virus (HCV) infectious virus cell culture model system has facilitated the development of whole-virus screening assays which can be used to interrogate the entire virus life cycle. Here, we describe the development of an HCV growth assay capable of identifying...

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Detalles Bibliográficos
Autores principales: Wichroski, Michael J., Fang, Jie, Eggers, Betsy J., Rose, Ronald E., Mazzucco, Charles E., Pokornowski, Kevin A., Baldick, Carl J., Anthony, Monique N., Dowling, Craig J., Barber, Lauren E., Leet, John E., Beno, Brett R., Gerritz, Samuel W., Agler, Michele L., Cockett, Mark I., Tenney, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412796/
https://www.ncbi.nlm.nih.gov/pubmed/22880053
http://dx.doi.org/10.1371/journal.pone.0042609

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