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Effective Elicitation of Human Effector CD8(+) T Cells in HLA-B*51:01 Transgenic Humanized Mice after Infection with HIV-1

Humanized mice are expected to be useful as small animal models for in vivo studies on the pathogenesis of infectious diseases. However, it is well known that human CD8(+) T cells cannot differentiate into effector cells in immunodeficient mice transplanted with only human CD34(+) hematopoietic stem...

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Detalles Bibliográficos
Autores principales:	Sato, Yoshinori, Nagata, Sayaka, Takiguchi, Masafumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412802/ https://www.ncbi.nlm.nih.gov/pubmed/22880104 http://dx.doi.org/10.1371/journal.pone.0042776

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