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The Role of the Subthalamic Nucleus in L-DOPA Induced Dyskinesia in 6-Hydroxydopamine Lesioned Rats

L-DOPA is the most effective treatment for Parkinson's disease (PD), but prolonged use leads to disabling motor complications including dyskinesia. Strong evidence supports a role of the subthalamic nucleus (STN) in the pathophysiology of PD whereas its role in dyskinesia is a matter of controv...

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Detalles Bibliográficos
Autores principales: Aristieta, Asier, Azkona, Garikoitz, Sagarduy, Ainhoa, Miguelez, Cristina, Ruiz-Ortega, José Ángel, Sanchez-Pernaute, Rosario, Ugedo, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412805/
https://www.ncbi.nlm.nih.gov/pubmed/22880070
http://dx.doi.org/10.1371/journal.pone.0042652

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