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The Role of the Subthalamic Nucleus in L-DOPA Induced Dyskinesia in 6-Hydroxydopamine Lesioned Rats
L-DOPA is the most effective treatment for Parkinson's disease (PD), but prolonged use leads to disabling motor complications including dyskinesia. Strong evidence supports a role of the subthalamic nucleus (STN) in the pathophysiology of PD whereas its role in dyskinesia is a matter of controv...
Autores principales: | Aristieta, Asier, Azkona, Garikoitz, Sagarduy, Ainhoa, Miguelez, Cristina, Ruiz-Ortega, José Ángel, Sanchez-Pernaute, Rosario, Ugedo, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412805/ https://www.ncbi.nlm.nih.gov/pubmed/22880070 http://dx.doi.org/10.1371/journal.pone.0042652 |
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