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The Guanine-Quadruplex Structure in the Human c-myc Gene's Promoter Is Converted into B-DNA Form by the Human Poly(ADP-Ribose)Polymerase-1

The important regulatory role of the guanine-quadruplex (GQ) structure, present in the nuclease hypersensitive element (NHE) III(1) region of the human c-myc (h c-myc) gene's promoter, in the regulation of the transcription of that gene has been documented. Here we present evidences, that the h...

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Detalles Bibliográficos
Autores principales: Fekete, Anna, Kenesi, Erzsebet, Hunyadi-Gulyas, Eva, Durgo, Hajnalka, Berko, Barbara, Dunai, Zsuzsanna A., Bauer, Pal I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412819/
https://www.ncbi.nlm.nih.gov/pubmed/22880082
http://dx.doi.org/10.1371/journal.pone.0042690

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