Cargando…

Adenoviral Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses after Cell Transplantation

Adult mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential which makes them attractive targets for regenerative medicine applications. However, to date, therapeutic success of MSC-therapy is limited and the genetic modification of MSCs using viral vectors is one opt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Treacy, Oliver, Ryan, Aideen E., Heinzl, Teresa, O'Flynn, Lisa, Cregg, Marese, Wilk, Mieszko, Odoardi, Francesca, Lohan, Paul, O'Brien, Timothy, Nosov, Mikhail, Ritter, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412834/ https://www.ncbi.nlm.nih.gov/pubmed/22880073 http://dx.doi.org/10.1371/journal.pone.0042662

Ejemplares similares

Immunogenicity of allogeneic mesenchymal stem cells
por: Schu, Sabine, et al.
Publicado: (2012)

Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?
por: Lohan, Paul, et al.
Publicado: (2017)

Targeted Adenoviral Vectors I: Transductional Targeting
por: Dmitriev, Igor P., et al.
Publicado: (2016)

Coating with spermine-pullulan polymer enhances adenoviral transduction of mesenchymal stem cells
por: Wan, Li, et al.
Publicado: (2016)

Regulating Immunogenicity and Tolerogenicity of Bone Marrow-Derived Dendritic Cells through Modulation of Cell Surface Glycosylation by Dexamethasone Treatment
por: Lynch, Kevin, et al.
Publicado: (2017)

Effects of Adenoviral Gene Transduction on the Stemness of Human Bone Marrow Mesenchymal Stem Cells
por: Marasini, Subash, et al.
Publicado: (2017)

K2 Transfection System Boosts the Adenoviral Transduction of Murine Mesenchymal Stromal Cells
por: Dumitrescu, Madalina, et al.
Publicado: (2021)

Efficacy of retroviral gene transfer into synovial fibroblasts is reduced by co-transduction with adenoviral vectors
por: Müller-Ladner, U, et al.
Publicado: (2002)

Third-Party Allogeneic Mesenchymal Stromal Cells Prevent Rejection in a Pre-sensitized High-Risk Model of Corneal Transplantation
por: Lohan, Paul, et al.
Publicado: (2018)

Vulvar Aphthous Ulcer in an Adolescent After Pfizer-BioNTech (BNT162b2) COVID-19 Vaccination
por: Wojcicki, Anna V., et al.
Publicado: (2022)

vIL-10-overexpressing human MSCs modulate naïve and activated T lymphocytes following induction of collagenase-induced osteoarthritis
por: Farrell, Eric, et al.
Publicado: (2016)

Effect of CGRP-Adenoviral Vector Transduction on the Osteoblastic Differentiation of Rat Adipose-Derived Stem Cells
por: Fang, Zhong, et al.
Publicado: (2013)

A novel reverse transduction adenoviral array for the functional analysis of shRNA libraries
por: Oehmig, Angelika, et al.
Publicado: (2008)

Transduction of ovarian cancer cells: a recombinant adeno-associated viral vector compared to an adenoviral vector
por: Vermeij, J, et al.
Publicado: (2001)

Subconjunctival administration of low-dose murine allogeneic mesenchymal stromal cells promotes corneal allograft survival in mice
por: Treacy, Oliver, et al.
Publicado: (2021)

Evaluation of signal transduction pathways after transient cutaneous adenoviral gene delivery
por: Steinstraesser, Lars, et al.
Publicado: (2011)

Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells
por: Liu, Shihai, et al.
Publicado: (2009)

A cost-effective method to enhance adenoviral transduction of primary murine osteoblasts and bone marrow stromal cells
por: Buo, Atum M, et al.
Publicado: (2016)

Functional magnetic resonance: biomarkers of response in breast cancer
por: O'Flynn, Elizabeth AM, et al.
Publicado: (2011)

Aging, cardiorespiratory fitness and sympathetic transduction
por: O’Brien, Myles W., et al.
Publicado: (2022)

Adenoviral Transduction of Human Acid Sphingomyelinase into Neo-Angiogenic Endothelium Radiosensitizes Tumor Cure
por: Stancevic, Branka, et al.
Publicado: (2013)

Correction: Functional magnetic resonance: biomarkers of response in breast cancer
por: O'Flynn, Elizabeth AM, et al.
Publicado: (2011)

Adenoviral Producer Cells
por: Kovesdi, Imre, et al.
Publicado: (2010)

Low Dose Histone Deacetylase Inhibitor, Depsipeptide (FR901228), Promotes Adenoviral Transduction in Human Rhabdomyosarcoma Cell Lines
por: Navid, Fariba, et al.
Publicado: (2004)

Commentary: A Cost-Effective Method to Enhance Adenoviral Transduction of Primary Murine Osteoblasts and Bone Marrow Stromal Cells
por: Sharma, Aikta, et al.
Publicado: (2020)

Immunization with whole cell but not acellular pertussis vaccines primes CD4 T(RM) cells that sustain protective immunity against nasal colonization with Bordetella pertussis
por: Wilk, Mieszko M., et al.
Publicado: (2019)

Novel adenoviral serotype 5 based immunotherapeutic induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients
por: Morse, Michael, et al.
Publicado: (2013)

A 3D View of Colorectal Cancer Models in Predicting Therapeutic Responses and Resistance
por: Reidy, Eileen, et al.
Publicado: (2021)

Administration of Human Non-Diabetic Mesenchymal Stromal Cells to a Murine Model of Diabetic Fracture Repair: A Pilot Study
por: Watson, Luke, et al.
Publicado: (2020)

Impaired neutralising antibody formation and high transduction efficacy after isolated hepatic perfusion with adenoviral vectors
por: van Etten, B, et al.
Publicado: (2004)

Ocular Localization and Transduction by Adenoviral Vectors Are Serotype-Dependent and Can Be Modified by Inclusion of RGD Fiber Modifications
por: Ueyama, Kazuhiro, et al.
Publicado: (2014)

Adenoviral SARS vaccine induces immune responses in monkeys
Publicado: (2013)

Pandemic-response adenoviral vector and RNA vaccine manufacturing
por: Kis, Zoltán, et al.
Publicado: (2022)

Functional imaging biomarkers for assessing response to treatment in liver and lung metastases
por: Bernardin, Livia, et al.
Publicado: (2013)

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations
por: Maggio, Ignazio, et al.
Publicado: (2016)

Azithromycin Clears Bordetella pertussis Infection in Mice but Also Modulates Innate and Adaptive Immune Responses and T Cell Memory
por: Borkner, Lisa, et al.
Publicado: (2018)

SUN-LB16 Clitoromegaly in Premature Infants: Is It Truly Pathologic?
por: Gupta, Meenal, et al.
Publicado: (2020)

Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?
por: O'Malley, Grace, et al.
Publicado: (2016)

Empowering analysts to undertake ethically and legally appropriate public good research.
por: O'Flynn, Lily
Publicado: (2022)

Changes in immunological profile of allogeneic mesenchymal stem cells after differentiation: should we be concerned?
por: Lohan, Paul, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_cu71o7vn8kr0qr9drnm21m93fs