Reversible Adaptive Plasticity: A Mechanism for Neuroblastoma Cell Heterogeneity and Chemo-Resistance

We describe a novel form of tumor cell plasticity characterized by reversible adaptive plasticity in murine and human neuroblastoma. Two cellular phenotypes were defined by their ability to exhibit adhered, anchorage dependent (AD) or sphere forming, anchorage independent (AI) growth. The tumor cell...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Lina, Abou-Antoun, Thamara, Vukmanovic, Stanislav, Sandler, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412992/
https://www.ncbi.nlm.nih.gov/pubmed/22891161
http://dx.doi.org/10.3389/fonc.2012.00082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412992/
https://www.ncbi.nlm.nih.gov/pubmed/22891161
http://dx.doi.org/10.3389/fonc.2012.00082

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