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Metabotropic glutamate receptors inhibit microglial glutamate release

Pro-inflammatory stimuli evoke an export of glutamate from microglia that is sufficient to contribute to excitotoxicity in neighbouring neurons. Since microglia also express various glutamate receptors themselves, we were interested in the potential feedback of glutamate on this system. Several agon...

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Detalles Bibliográficos
Autores principales: McMullan, Stephen M, Phanavanh, Bounleut, Guo Li, Gary, Barger, Steven W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Neurochemistry 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413012/
https://www.ncbi.nlm.nih.gov/pubmed/22770428
http://dx.doi.org/10.1042/AN20120044