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Management of antipsychotic treatment discontinuation and interruptions using model-based simulations

BACKGROUND: Medication nonadherence is a well described and prevalent clinical occurrence in schizophrenia. These pharmacokinetic model-based simulations analyze predicted antipsychotic plasma concentrations in nonadherence and treatment interruption scenarios and with treatment reinitiation. METHOD...

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Detalles Bibliográficos
Autores principales:	Samtani, Mahesh N, Sheehan, John J, Fu, Dong-Jing, Remmerie, Bart, Sliwa, Jennifer Kern, Alphs, Larry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413023/ https://www.ncbi.nlm.nih.gov/pubmed/22888277 http://dx.doi.org/10.2147/CPAA.S32735

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