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Transgenerational Effects of Prenatal Synthetic Glucocorticoids on Hypothalamic-Pituitary-Adrenal Function

Approximately 10% of pregnant women are at risk of preterm delivery and receive synthetic glucocorticoids (sGC) to promote fetal lung development. Studies have indicated that prenatal sGC therapy modifies hypothalamic-pituitary-adrenal (HPA) function in first-generation (F(1)) offspring. The objecti...

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Detalles Bibliográficos
Autores principales:	Iqbal, Majid, Moisiadis, Vasilis G., Kostaki, Alisa, Matthews, Stephen G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2012
Materias:	Glucocorticoids-CRH-ACTH-Adrenal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413075/ https://www.ncbi.nlm.nih.gov/pubmed/22564976 http://dx.doi.org/10.1210/en.2012-1054

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