Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease

Restriction endonuclease Bse634I recognizes and cleaves the degenerate DNA sequence 5′-R/CCGGY-3′ (R stands for A or G; Y for T or C, ‘/’ indicates a cleavage position). Here, we report the crystal structures of the Bse634I R226A mutant complexed with cognate oligoduplexes containing ACCGGT and GCCG...

Descripción completa

Detalles Bibliográficos
Autores principales: Manakova, Elena, Gražulis, Saulius, Zaremba, Mindaugas, Tamulaitiene, Giedre, Golovenko, Dmitrij, Siksnys, Virginijus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413111/
https://www.ncbi.nlm.nih.gov/pubmed/22495930
http://dx.doi.org/10.1093/nar/gks300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413111/
https://www.ncbi.nlm.nih.gov/pubmed/22495930
http://dx.doi.org/10.1093/nar/gks300

Ejemplares similares