Computational inference of mRNA stability from histone modification and transcriptome profiles

Histone modifications play important roles in regulating eukaryotic gene expression and have been used to model expression levels. Here, we present a regression model to systematically infer mRNA stability by comparing transcriptome profiles with ChIP-seq of H3K4me3, H3K27me3 and H3K36me3. The resul...

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Detalles Bibliográficos
Autores principales: Wang, Chengyang, Tian, Rui, Zhao, Qian, Xu, Han, Meyer, Clifford A., Li, Cheng, Zhang, Yong, Liu, X. Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413115/
https://www.ncbi.nlm.nih.gov/pubmed/22495509
http://dx.doi.org/10.1093/nar/gks304

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