Cargando…
The transition in spliceosome assembly from complex E to complex A purges surplus U1 snRNPs from alternative splice sites
Spliceosomes are assembled in stages. The first stage forms complex E, which is characterized by the presence of U1 snRNPs base-paired to the 5′ splice site, components recognizing the 3′ splice site and proteins thought to connect them. The splice sites are held in close proximity and the pre-mRNA...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413131/ https://www.ncbi.nlm.nih.gov/pubmed/22505580 http://dx.doi.org/10.1093/nar/gks322 |