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KH domains with impaired nucleic acid binding as a tool for functional analysis
In eukaryotes, RNA-binding proteins that contain multiple K homology (KH) domains play a key role in coordinating the different steps of RNA synthesis, metabolism and localization. Understanding how the different KH modules participate in the recognition of the RNA targets is necessary to dissect th...
Autores principales: | Hollingworth, David, Candel, Adela M., Nicastro, Giuseppe, Martin, Stephen R., Briata, Paola, Gherzi, Roberto, Ramos, Andres |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413153/ https://www.ncbi.nlm.nih.gov/pubmed/22547390 http://dx.doi.org/10.1093/nar/gks368 |
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