Structural and biochemical characterization of a trapped coenzyme A adduct of Caenorhabditis elegans glucosamine-6-phosphate N-acetyltransferase 1

Glucosamine-6-phosphate N-acetyltransferase 1 (GNA1) produces GlcNAc-6-phosphate from GlcN-6-phosphate and acetyl coenzyme A. Early mercury-labelling experiments implicated a conserved cysteine in the reaction mechanism, whereas recent structural data appear to support a mechanism in which this cyst...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorfmueller, Helge C., Fang, Wenxia, Rao, Francesco V., Blair, David E., Attrill, Helen, van Aalten, Daan M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413214/
https://www.ncbi.nlm.nih.gov/pubmed/22868768
http://dx.doi.org/10.1107/S0907444912019592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413214/
https://www.ncbi.nlm.nih.gov/pubmed/22868768
http://dx.doi.org/10.1107/S0907444912019592

Ejemplares similares