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Structural and biochemical characterization of a trapped coenzyme A adduct of Caenorhabditis elegans glucosamine-6-phosphate N-acetyltransferase 1
Glucosamine-6-phosphate N-acetyltransferase 1 (GNA1) produces GlcNAc-6-phosphate from GlcN-6-phosphate and acetyl coenzyme A. Early mercury-labelling experiments implicated a conserved cysteine in the reaction mechanism, whereas recent structural data appear to support a mechanism in which this cyst...
Autores principales: | Dorfmueller, Helge C., Fang, Wenxia, Rao, Francesco V., Blair, David E., Attrill, Helen, van Aalten, Daan M. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413214/ https://www.ncbi.nlm.nih.gov/pubmed/22868768 http://dx.doi.org/10.1107/S0907444912019592 |
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