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HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly
To produce progeny virus, human immunodeficiency virus type I (HIV-1) Gag assembles into capsids that package the viral genome and bud from the infected cell. During assembly of immature capsids, Gag traffics through a pathway of assembly intermediates (AIs) that contain the cellular adenosine triph...
Autores principales: | Reed, Jonathan C., Molter, Britta, Geary, Clair D., McNevin, John, McElrath, Julie, Giri, Samina, Klein, Kevin C., Lingappa, Jaisri R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413349/ https://www.ncbi.nlm.nih.gov/pubmed/22851315 http://dx.doi.org/10.1083/jcb.201111012 |
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