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A first line of defense against ER stress

BiP is the predominant DnaK/Hsp70-type chaperone protein in the ER. It is required for folding and assembling newly synthesized ER client proteins, yet having too much BiP inhibits folding. In this issue, Chambers et al. (2012. J. Cell Biol. doi:10.1083/jcb.201202005) report that ADP ribosylation of...

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Detalles Bibliográficos
Autores principales:	Pincus, David, Walter, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413362/ https://www.ncbi.nlm.nih.gov/pubmed/22869593 http://dx.doi.org/10.1083/jcb.201207076

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