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Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy

Microtubules are dynamic polymers that stochastically switch between growing and shrinking phases. Microtubule dynamics are regulated by guanosine triphosphate (GTP) hydrolysis by β-tubulin, but the mechanism of this regulation remains elusive because high-resolution microtubule structures have only...

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Detalles Bibliográficos
Autores principales:	Yajima, Hiroaki, Ogura, Toshihiko, Nitta, Ryo, Okada, Yasushi, Sato, Chikara, Hirokawa, Nobutaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413364/ https://www.ncbi.nlm.nih.gov/pubmed/22851320 http://dx.doi.org/10.1083/jcb.201201161

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