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Smad7 siRNA inhibit expression of extracellular matrix in trabecular meshwork cells treated with TGF-β2

PURPOSE: Extracellular matrix (ECM) deposits lead to elevated resistance of aqueous humor outflow which play an important role in the development of primary open angle glaucoma (POAG). The TGF-β2 (transforming growth factor β)/Smad (signaling mathers against decapentaplegic) pathway is known to regu...

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Detalles Bibliográficos
Autores principales:	Su, Ying, Yang, Chen-Yuan C., Li, Zhongrui, Xu, Feng, Zhang, Lei, Wang, Feng, Zhao, Shiguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413437/ https://www.ncbi.nlm.nih.gov/pubmed/22876112

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