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Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial

BACKGROUND: In 2005, the Democratic Republic of Congo (DRC) adopted artesunate and amodiaquine (ASAQ) as first-line anti-malarial treatment. In order to compare the efficacy of the fixed-dose formulation ASAQ versus artemether-lumefantrine (AL), a randomized, non-inferiority open-label trial was con...

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Detalles Bibliográficos
Autores principales: Espié, Emmanuelle, Lima, Angeles, Atua, Benjamin, Dhorda, Mehul, Flévaud, Laurence, Sompwe, Eric M, Palma Urrutia, Pedro Pablo, Guerin, Philippe J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413505/
https://www.ncbi.nlm.nih.gov/pubmed/22631564
http://dx.doi.org/10.1186/1475-2875-11-174