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Identification of DNA Binding Motifs of the Mycobacterium tuberculosis PhoP/PhoR Two-Component Signal Transduction System

BACKGROUND: The Mycobacterium tuberculosis PhoP/PhoR two-component signal transduction system controls the expression of about 2% of the genome and plays a major role in pathogenicity. However, its regulon has not been well characterized. METHODOLOGY/PRINCIPAL FINDINGS: The binding site of PhoP tran...

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Detalles Bibliográficos
Autores principales: Cimino, Mena, Thomas, Christophe, Namouchi, Amine, Dubrac, Sarah, Gicquel, Brigitte, Gopaul, Deshmukh N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413638/
https://www.ncbi.nlm.nih.gov/pubmed/22880126
http://dx.doi.org/10.1371/journal.pone.0042876