Presynaptic Selectivity of a Ligand for Serotonin 1A Receptors Revealed by In Vivo PET Assays of Rat Brain

A novel investigational antidepressant with high affinity for the serotonin transporter and the serotonin 1A (5-HT(1A)) receptor, called Wf-516 (structural formula: (2S)-1-[4-(3,4-dichlorophenyl)piperidin-1-yl]-3-[2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol monohydrochloride),...

Descripción completa

Detalles Bibliográficos
Autores principales: Saijo, Takeaki, Maeda, Jun, Okauchi, Takashi, Maeda, Jun-ichi, Morio, Yasunori, Kuwahara, Yasuhiro, Suzuki, Masayuki, Goto, Nobuharu, Fukumura, Toshimitsu, Suhara, Tetsuya, Higuchi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413639/
https://www.ncbi.nlm.nih.gov/pubmed/22880045
http://dx.doi.org/10.1371/journal.pone.0042589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413639/
https://www.ncbi.nlm.nih.gov/pubmed/22880045
http://dx.doi.org/10.1371/journal.pone.0042589

Ejemplares similares