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Presynaptic Selectivity of a Ligand for Serotonin 1A Receptors Revealed by In Vivo PET Assays of Rat Brain
A novel investigational antidepressant with high affinity for the serotonin transporter and the serotonin 1A (5-HT(1A)) receptor, called Wf-516 (structural formula: (2S)-1-[4-(3,4-dichlorophenyl)piperidin-1-yl]-3-[2-(5-methyl-1,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol monohydrochloride),...
Autores principales: | Saijo, Takeaki, Maeda, Jun, Okauchi, Takashi, Maeda, Jun-ichi, Morio, Yasunori, Kuwahara, Yasuhiro, Suzuki, Masayuki, Goto, Nobuharu, Fukumura, Toshimitsu, Suhara, Tetsuya, Higuchi, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413639/ https://www.ncbi.nlm.nih.gov/pubmed/22880045 http://dx.doi.org/10.1371/journal.pone.0042589 |
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