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A VLP Vaccine Induces Broad-Spectrum Cross-Protective Antibody Immunity against H5N1 and H1N1 Subtypes of Influenza A Virus
The recent threats of influenza epidemics and pandemics have prioritized the development of a universal vaccine that offers protection against a wider variety of influenza infections. Here, we demonstrate a genetically modified virus-like particle (VLP) vaccine, referred to as H5M2eN1-VLP, that incr...
Autores principales: | Wu, Chia-Ying, Yeh, Yi-Chun, Chan, Jia-Tsrong, Yang, Yu-Chih, Yang, Ji-Rong, Liu, Ming-Tsan, Wu, Ho-Sheng, Hsiao, Pei-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413679/ https://www.ncbi.nlm.nih.gov/pubmed/22879951 http://dx.doi.org/10.1371/journal.pone.0042363 |
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