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PAM50 assay and the three-gene model for identifying the major and clinically relevant molecular subtypes of breast cancer

It has recently been proposed that a three-gene model (SCMGENE) that measures ESR1, ERBB2, and AURKA identifies the major breast cancer intrinsic subtypes and provides robust discrimination for clinical use in a manner very similar to a 50-gene subtype predictor (PAM50). However, the clinical releva...

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Detalles Bibliográficos
Autores principales: Prat, A., Parker, J. S., Fan, C., Perou, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413822/
https://www.ncbi.nlm.nih.gov/pubmed/22752290
http://dx.doi.org/10.1007/s10549-012-2143-0