Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families

Drug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after drug-resistant tuberculosis was identified in...

Descripción completa

Detalles Bibliográficos
Autores principales: Seddon, James A., Warren, Rob M., Enarson, Donald A., Beyers, Nulda, Schaaf, H. Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2012
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414024/
https://www.ncbi.nlm.nih.gov/pubmed/22840848
http://dx.doi.org/10.3201/eid1808.111650
Descripción
Sumario:Drug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after drug-resistant tuberculosis was identified in 2 children. The findings demonstrate the potential for resistance to be transmitted and amplified within families.

Ejemplares similares