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3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol
In the title compound, C(24)H(19)N(3)O, the pyrazole ring is close to being planar (r.m.s. deviation of the five fitted atoms = 0.062 Å), and each of the N-bound quinoline ring [dihedral angle = 9.90 (7)°] and the C-bound phenyl ring in the 3-position is close to being coplanar [dihedral angle = 8.8...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414180/ https://www.ncbi.nlm.nih.gov/pubmed/22904787 http://dx.doi.org/10.1107/S1600536812029340 |
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author | Najib, Muhd. Hidayat bin Tan, Ai Ling Young, David J. Ng, Seik Weng Tiekink, Edward R. T. |
author_facet | Najib, Muhd. Hidayat bin Tan, Ai Ling Young, David J. Ng, Seik Weng Tiekink, Edward R. T. |
author_sort | Najib, Muhd. Hidayat bin |
collection | PubMed |
description | In the title compound, C(24)H(19)N(3)O, the pyrazole ring is close to being planar (r.m.s. deviation of the five fitted atoms = 0.062 Å), and each of the N-bound quinoline ring [dihedral angle = 9.90 (7)°] and the C-bound phenyl ring in the 3-position is close to being coplanar [dihedral angle = 8.87 (9)°]. However, the phenyl ring in the 5-position forms a dihedral angle of 72.31 (9)°. The hydroxy group forms an intramolecular hydrogen bond to the quinoline N atom. In the crystal, molecules are connected into supramolecular layers two molecules thick in the bc plane by C—H⋯O and C—H⋯π interactions. |
format | Online Article Text |
id | pubmed-3414180 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-34141802012-08-17 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol Najib, Muhd. Hidayat bin Tan, Ai Ling Young, David J. Ng, Seik Weng Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(19)N(3)O, the pyrazole ring is close to being planar (r.m.s. deviation of the five fitted atoms = 0.062 Å), and each of the N-bound quinoline ring [dihedral angle = 9.90 (7)°] and the C-bound phenyl ring in the 3-position is close to being coplanar [dihedral angle = 8.87 (9)°]. However, the phenyl ring in the 5-position forms a dihedral angle of 72.31 (9)°. The hydroxy group forms an intramolecular hydrogen bond to the quinoline N atom. In the crystal, molecules are connected into supramolecular layers two molecules thick in the bc plane by C—H⋯O and C—H⋯π interactions. International Union of Crystallography 2012-07-04 /pmc/articles/PMC3414180/ /pubmed/22904787 http://dx.doi.org/10.1107/S1600536812029340 Text en © Najib et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Najib, Muhd. Hidayat bin Tan, Ai Ling Young, David J. Ng, Seik Weng Tiekink, Edward R. T. 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol |
title | 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol |
title_full | 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol |
title_fullStr | 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol |
title_full_unstemmed | 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol |
title_short | 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol |
title_sort | 3,5-diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1h-pyrazol-5-ol |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414180/ https://www.ncbi.nlm.nih.gov/pubmed/22904787 http://dx.doi.org/10.1107/S1600536812029340 |
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