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3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol

In the title compound, C(24)H(19)N(3)O, the pyrazole ring is close to being planar (r.m.s. deviation of the five fitted atoms = 0.062 Å), and each of the N-bound quinoline ring [dihedral angle = 9.90 (7)°] and the C-bound phenyl ring in the 3-position is close to being coplanar [dihedral angle = 8.8...

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Detalles Bibliográficos
Autores principales: Najib, Muhd. Hidayat bin, Tan, Ai Ling, Young, David J., Ng, Seik Weng, Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414180/
https://www.ncbi.nlm.nih.gov/pubmed/22904787
http://dx.doi.org/10.1107/S1600536812029340
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author Najib, Muhd. Hidayat bin
Tan, Ai Ling
Young, David J.
Ng, Seik Weng
Tiekink, Edward R. T.
author_facet Najib, Muhd. Hidayat bin
Tan, Ai Ling
Young, David J.
Ng, Seik Weng
Tiekink, Edward R. T.
author_sort Najib, Muhd. Hidayat bin
collection PubMed
description In the title compound, C(24)H(19)N(3)O, the pyrazole ring is close to being planar (r.m.s. deviation of the five fitted atoms = 0.062 Å), and each of the N-bound quinoline ring [dihedral angle = 9.90 (7)°] and the C-bound phenyl ring in the 3-position is close to being coplanar [dihedral angle = 8.87 (9)°]. However, the phenyl ring in the 5-position forms a dihedral angle of 72.31 (9)°. The hy­droxy group forms an intra­molecular hydrogen bond to the quinoline N atom. In the crystal, mol­ecules are connected into supra­molecular layers two mol­ecules thick in the bc plane by C—H⋯O and C—H⋯π inter­actions.
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spelling pubmed-34141802012-08-17 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol Najib, Muhd. Hidayat bin Tan, Ai Ling Young, David J. Ng, Seik Weng Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(19)N(3)O, the pyrazole ring is close to being planar (r.m.s. deviation of the five fitted atoms = 0.062 Å), and each of the N-bound quinoline ring [dihedral angle = 9.90 (7)°] and the C-bound phenyl ring in the 3-position is close to being coplanar [dihedral angle = 8.87 (9)°]. However, the phenyl ring in the 5-position forms a dihedral angle of 72.31 (9)°. The hy­droxy group forms an intra­molecular hydrogen bond to the quinoline N atom. In the crystal, mol­ecules are connected into supra­molecular layers two mol­ecules thick in the bc plane by C—H⋯O and C—H⋯π inter­actions. International Union of Crystallography 2012-07-04 /pmc/articles/PMC3414180/ /pubmed/22904787 http://dx.doi.org/10.1107/S1600536812029340 Text en © Najib et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Najib, Muhd. Hidayat bin
Tan, Ai Ling
Young, David J.
Ng, Seik Weng
Tiekink, Edward R. T.
3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol
title 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol
title_full 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol
title_fullStr 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol
title_full_unstemmed 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol
title_short 3,5-Diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1H-pyrazol-5-ol
title_sort 3,5-diphenyl-1-(quinolin-2-yl)-4,5-dihydro-1h-pyrazol-5-ol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414180/
https://www.ncbi.nlm.nih.gov/pubmed/22904787
http://dx.doi.org/10.1107/S1600536812029340
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