Effect of molecular weight of polyethyleneimine on loading of CpG oligodeoxynucleotides onto flake-shell silica nanoparticles for enhanced TLR9-mediated induction of interferon-α

BACKGROUND: Class B CpG oligodeoxynucleotides primarily interact with Toll-like receptor 9 (TLR9) in B cells and enhance the immune system through induction of various interleukins including interleukin-6 in these immune cells. Although free class B CpG oligodeoxynucleotides do not induce interferon...

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Detalles Bibliográficos
Autores principales: Manoharan, Yuvaraj, Ji, Qingmin, Yamazaki, Tomohiko, Chinnathambi, Shanmugavel, Chen, Song, Ganesan, Singaravelu, Hill, Jonathan P, Ariga, Katsuhiko, Hanagata, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414203/
https://www.ncbi.nlm.nih.gov/pubmed/22888224
http://dx.doi.org/10.2147/IJN.S32592

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